News

24 april 2024

BIG APPLE is looking for participating centers

The BIG APPLE study has started recruiting patients and is looking for participating centers in the Netherlands and beyond. Interested? Contact us at bigapple@amsterdamumc.nl or use the contact form below!

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13 februari 2024

GENERATOR is looking for participating centers

The GENERATOR study has started recruiting patients in multiple centers and is looking for participating centers in the Netherlands and beyond. Interested? Contact us at generator@amsterdamumc.nl or use the contact form below!

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15 januari 2024

400 patients included in the CONFIDENCE trial!

400 patients have now been included in the trial!

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13 november 2023

GENERATOR study looking for participating centers

The GENERATOR study received ethical approval in the Netherlands and will start patient recruitment in the Amsterdam UMC in November 2023. We are looking for Dutch and international centers to join the team. This trial is conducted and coordinated by the PROVEnetwork.

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13 november 2023

GENERATOR Ethical approval institutional review board

The GENERATOR project has received ethical approval from the institutional review board of the Amsterdam University Medical Centers. The first patient is expected to be enrolled in November 2023

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9 oktober 2023

Second steering committee meeting - September 27th

The second steering committee meeting took place on Wednesday September 27th. We shared the results of the pilot studies and discussed the upcoming steps. Please find the presentation below, under the header 'documents'.

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26 september 2023

Second steering committee meeting on September 27th

The second PRoVENT-PED steering committee meeting will take place on Wednesday September 27th, to share the results of the pilot studies and to discuss the upcoming steps.

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26 september 2023

PRoVENT-PED has started.

We are currently performing the pilot studies for feasibility in two Dutch hospitals: the Amsterdam University Medical Center (AUMC) and the University Medical Center of Groningen (UMCG). Furthermore, we started with recruiting centers, national coordinators and local coordinators who are interested in participating.

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26 september 2023

The PRoVENT-PED protocol has been approved by the Institutional Review Board.

The PRoVENT-PED protocol has been approved by the Institutional Review Board in July 2023.

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9 augustus 2023

200 CONFIDENCE patients included

200 patients have been included in the CONFIDENCE trial! With the start of new centers, inclusion rate is increasing rapidly.

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8 augustus 2023

PRoFLUID pilot study concluded

A local pilot has been done for the PRoFLUID. The pilot included 45 invasively ventilated patients from the Amsterdam UMC during a 28 day inclusion period.

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8 augustus 2023

PRoFLUID registered on clinicaltrials.gov

PRoFLUID has been registered on clinicaltrials.gov

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14 juli 2023

PRoVENT-PED is in preparation

PRoVENT-PED is in preparation! In July 2023 we got the protocol approved by the METC.

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10 mei 2023

100 CONFIDENCE patients included

The hundredth patient was included in the trial!

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10 mei 2023

Publication of the CONFIDENCE trial protocol

The trial protocol has been published with open access in BioMedCentral Trials.

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6 januari 2023

Happy 2023!

Happy 2023 from the PEGASUS study team. We've started the new year with ethics approval in the Netherlands, Poland, Italy, Portugal, Denmark and Belgium! Early this year many centres in these countries will start patient inclusion. Based on the experience of the first 8 patients we included in Amsterdam, we are writing a detailed handbook on how to guide mechanical ventilation in PEGASUS patients.

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28 oktober 2022

Co-investigator meeting for the PEGASUS study

The first PEGASUS co-investigator meeting has been planned for the 5th of December 2022.

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17 oktober 2022

First patient in PEGASUS study

The first PEGASUS patient has been included in the Amsterdam UMC.

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